A clinical trial was conducted in the Netherlands to evaluate the effect of medical co-prescription of heroin and methadone on mental and physical health and social functioning of chronic treatment-resistant heroin-dependent patients

نویسندگان

  • Marjolein G. Klous
  • WeiChing Lee
  • Michel J. X. Hillebrand
  • Wim van den Brink
  • Jan M. van Ree
  • Jos H. Beijnen
چکیده

patients to any degradation products after inhaling volatilized heroin, especially because they were obtained from a controlled clinical trial using pharmaceutical heroin, eliminating the possible influence of impurities, diluents, and adulterants present in street heroin.

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منابع مشابه

Medical prescription of heroin to treatment resistant heroin addicts: two randomised controlled trials.

OBJECTIVE To determine whether supervised medical prescription of heroin can successfully treat addicts who do not sufficiently benefit from methadone maintenance treatment. DESIGN Two open label randomised controlled trials. SETTING Methadone maintenance programmes in six cities in the Netherlands. PARTICIPANTS 549 heroin addicts. INTERVENTIONS Inhalable heroin (n = 375) or injectable ...

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Outcome of long-term heroin-assisted treatment offered to chronic, treatment-resistant heroin addicts in the Netherlandsadd_2754

Aims To describe 4-year treatment retention and treatment response among chronic, treatment-resistant heroindependent patients offered long-term heroin-assisted treatment (HAT) in the Netherlands. Design Observational cohort study. Setting and intervention Out-patient treatment in specialized heroin treatment centres in six cities in the Netherlands, with methadone plus injectable or inhalable ...

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Outcome of long-term heroin-assisted treatment offered to chronic, treatment-resistant heroin addicts in the Netherlands.

AIMS To describe 4-year treatment retention and treatment response among chronic, treatment-resistant heroin-dependent patients offered long-term heroin-assisted treatment (HAT) in the Netherlands. DESIGN Observational cohort study. SETTING AND INTERVENTION Out-patient treatment in specialized heroin treatment centres in six cities in the Netherlands, with methadone plus injectable or inhal...

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The Effectiveness of Group Therapy on the Family Functioning of Individuals under Methadone Treatment: A Clinical Trial

Background: A significant number of opioid-dependent patients in Iran are now being treated by methadone maintenance therapy (MMT). One of the social complications of substance dependency is family disorganization and a decrease in marital satisfaction. This study aimed to determine the effect of group therapy based on the transtheoretical model of change on family functioning of the patients u...

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Supervised co-prescription of heroin to treatment-resistant heroin addicts is more effective than treatment with methadone alone.

van den Brink W, Hendriks VM, Blanken P, et al. Medical prescription of heroin to treatment resistant heroin addicts: two randomised controlled trials. BMJ 2003;327:310. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ....

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تاریخ انتشار 2006